What is meant by microdosing of Suboxone? The main medication in Suboxone is buprenorphine, given to treat opioid use disorder. It works by fitting into opioid receptors, tiny structures in the brain and throughout the body. When buprenorphine is in the opioid receptors, opioids such as heroin and fentanyl cannot reach the receptors easily, and euphoria, or a “high,” cannot be achieved. This helps patients lose their craving for opioids and stop using them.
When Suboxone is taken while the problematic drug is still in the system, the buprenorphine will replace the opioid already present. This can lead to withdrawal symptoms. For this reason, unless patients can wait long enough for the drug being misused to leave their systems entirely, Suboxone can be given in frequent microdoses. This can limit symptoms of withdrawal. Discuss with your physician whether waiting for a standard dose or microdosing is the better option for you.